Article
HbF in HbE/β-thalassemia: A clinical and laboratory correlation.
Hematology (Amsterdam, Netherlands) - 1 Jul 2015
Lim Wai Feng, Muniandi Logeswaran, George Elizabeth, Sathar Jameela, Teh Lai Kuan, Lai Mei I
Abstract excerpt
INTRODUCTION: Fetal hemoglobin (HbF) is the predominant hemoglobin in red cells during fetal life. Just after birth, the level of HbF decreases gradually to <1%, and is replaced mainly by adult hemoglobin (HbA) (∼ 97%). However, higher HbF levels could be associated with HbE/β-thalassemia, a complex thalassemia intermedia with a diverse clinical severity ranging from mild-to-severe anemia. This study investigates...
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