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Article

Effect of single amino acid mutations on function of Mycobacterium tuberculosis H37RV and H37RA by computational approaches.

The Indian journal of tuberculosis - 1 Jul 2014

Jena Lingaraja, Kashikar Supriya, Kumar Satish, Harinath Bhaskar C

Abstract excerpt

BACKGROUND: Studies have been reported on genomic analysis to explain virulence of MTB H37Rv vs. MTB H37Ra strain. Proteomic comparison analysis at our centre has shown variability of 244 proteins in MTB H37Rv. A single amino acid mutation in protein sequence may cause alteration in protein structure and function that may account for virulence and drug resistance properties of pathogenic organisms. AIM: To find...

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PMID: 25241568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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