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Article

Genetics insight into the amyotrophic lateral sclerosis/frontotemporal dementia spectrum.

Journal of medical genetics - 1 Mar 2017

Ji Ai-Ling, Zhang Xia, Chen Wei-Wei, Huang Wen-Juan

Abstract excerpt

Recent genetic discoveries have dramatically changed our understanding of two major neurodegenerative conditions. Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are common, devastating diseases of the brain. For decades, ALS and FTD were classified as movement and cognitive disorders, respectively, due to their distinct clinical phenotypes. The recent identification of chromosome 9 open...

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PMID: 28087719
DOI: 10.1136/jmedgenet-2016-104271

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