Article
Periostin gene variants are associated with disease course and severity in juvenile idiopathic arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Covone Angela Elvira, Solari Nicoletta, Malattia Clara, Pop Valentin, Martini Alberto, Ravelli Angelo, Ravazzolo Roberto
Abstract excerpt
OBJECTIVES: This study aimed to identify polymorphic variants of the Periostin gene associated with disease severity and clinical course in children with juvenile idiopathic arthritis. METHODS: DNA genotyping of 7 single-nucleotide polymorphisms within the periostin gene was performed in 117 patients and their parents and in 102 control samples. Our patients were divided in the following 4 disease categories: 1)...
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