Article
A polymorphic variant inside the osteopontin gene shows association with disease course in oligoarticular juvenile idiopathic arthritis.
Annals of the rheumatic diseases - 1 May 2006
Marciano R, Giacopelli F, Divizia M T, Gattorno M, Felici E, Pistorio A, Martini A, Ravazzolo R, Picco P
Abstract excerpt
BACKGROUND: Oligoarticular onset juvenile idiopathic arthritis (JIA) has a variable disease course. In some patients the disease remains confined to a few joints (persistent oligoarticular) while in others it extends to affect more joints (oligoarticular extended). Osteopontin is thought to play a role in the pathogenesis. OBJECTIVE: To investigate whether a polymorphic variant in the human osteopontin gene,...
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