Article
The tandem repeats enabling reversible switching between the two phases of β-lactamase substrate spectrum.
PLoS genetics - 1 Sept 2014
Yi Hyojeong, Song Han, Hwang Junghyun, Kim Karan, Nierman William C, Kim Heenam Stanley
Abstract excerpt
Expansion or shrinkage of existing tandem repeats (TRs) associated with various biological processes has been actively studied in both prokaryotic and eukaryotic genomes, while their origin and biological implications remain mostly unknown. Here we describe various duplications (de novo TRs) that occurred in the coding region of a β-lactamase gene, where a conserved structure called the omega loop is encoded....
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