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Plasmid-encoded gene duplications of extended-spectrum β-lactamases in clinical bacterial isolates

26 Feb 2024

Abstract excerpt

Introduction The emergence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is an urgent and alarming One Health problem. This study aimed to investigate duplications of plasmid-encoded ESBL genes and their impact on antimicrobial resistance (AMR) phenotypes in clinical and screening isolates. Methods Multi-drug-resistant bacteria from hospitalized patients were collected during routine...

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PMID: 38469349
DOI: 10.3389/fcimb.2024.1343858

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