Article
Molecular insights into the evolutionary pathway of Vibrio cholerae O1 atypical El Tor variants.
PLoS pathogens - 1 Sept 2014
Kim Eun Jin, Lee Dokyung, Moon Se Hoon, Lee Chan Hee, Kim Sang Jun, Lee Jae Hyun, Kim Jae Ouk, Song Manki, Das Bhabatosh, Clemens John D, Pape Jean William, Nair G Balakrish, Kim Dong Wook
Abstract excerpt
Pandemic V. cholerae strains in the O1 serogroup have 2 biotypes: classical and El Tor. The classical biotype strains of the sixth pandemic, which encode the classical type cholera toxin (CT), have been replaced by El Tor biotype strains of the seventh pandemic. The prototype El Tor strains that produce biotype-specific cholera toxin are being replaced by atypical El Tor variants that harbor classical cholera...
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