Article
A recalibrated molecular clock and independent origins for the cholera pandemic clones.
PloS one - 1 Jan 2008
Feng Lu, Reeves Peter R, Lan Ruiting, Ren Yi, Gao Chunxu, Zhou Zhemin, Ren Yan, Cheng Jiansong, Wang Wei, Wang Jianmei, Qian Wubin, Li Dan, Wang Lei
Abstract excerpt
Cholera, caused by Vibrio cholerae, erupted globally from South Asia in 7 pandemics, but there were also local outbreaks between the 6(th) (1899-1923) and 7(th) (1961-present) pandemics. All the above are serotype O1, whereas environmental or invertebrate isolates are antigenically diverse. The pre 7th pandemic isolates mentioned above, and other minor pathogenic clones, are related to the 7(th) pandemic clone,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.