Article
Lhx3 and Lhx4 suppress Kolmer-Agduhr interneuron characteristics within zebrafish axial motoneurons.
Development (Cambridge, England) - 1 Oct 2014
Seredick Steve, Hutchinson Sarah A, Van Ryswyk Liesl, Talbot Jared C, Eisen Judith S
Abstract excerpt
A central problem in development is how fates of closely related cells are segregated. Lineally related motoneurons (MNs) and interneurons (INs) express many genes in common yet acquire distinct fates. For example, in mouse and chick Lhx3 plays a pivotal role in the development of both cell classes. Here, we utilize the ability to recognize individual zebrafish neurons to examine the roles of Lhx3 and its paralog...
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