Article
Morphogenesis and cell fate determination within the adaxial cell equivalence group of the zebrafish myotome.
PLoS genetics - 1 Jan 2012
Nguyen-Chi Mai E, Bryson-Richardson Robert, Sonntag Carmen, Hall Thomas E, Gibson Abigail, Sztal Tamar, Chua Wendy, Schilling Thomas F, Currie Peter D
Abstract excerpt
One of the central questions of developmental biology is how cells of equivalent potential-an equivalence group-come to adopt specific cellular fates. In this study we have used a combination of live imaging, single cell lineage analyses, and perturbation of specific signaling pathways to dissect the specification of the adaxial cells of the zebrafish embryo. We show that the adaxial cells are myogenic precursors...
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