Notch signaling regulates neural precursor allocation and binary neuronal fate decisions in zebrafish.

Abstract excerpt

Notch signaling plays a well-described role in regulating the formation of neurons from proliferative neural precursors in vertebrates but whether, as in flies, it also specifies sibling cells for different neuronal fates is not known. Ventral spinal cord precursors called pMN cells produce mostly motoneurons and oligodendrocytes, but recent lineage-marking experiments reveal that they also make astrocytes,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Lineage
• Share to Developmental Biology
• Share to Interneurons