Article
Susceptibility to large-joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jan 2015
Etokebe Godfrey E, Jotanovic Zdravko, Mihelic Radovan, Mulac-Jericevic Biserka, Nikolic Tamara, Balen Sanja, Sestan Branko, Dembic Zlatko
Abstract excerpt
Family with sequence similarity 46, member A (FAM46A) gene VNTR and BCL2-Associated Athanogene 6 (BAG6) gene rs3117582 polymorphisms were genotyped in a case-control study with 474 large-joint (hip and knee) osteoarthritis (OA) patients and 568 controls in Croatian population by candidate-gene approach for association with OA. We found that BAG6 rs3117582 SNP genotypes were associated with protection (major...
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