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ORF-Interrupting Mutations in Monkeypox Virus Genomes from Washington and Ohio, 2022.

Viruses - 29 Oct 2022

Sereewit Jaydee, Lieberman Nicole A P, Xie Hong, Bakhash Shah A K Mohamed, Nunley B Ethan, Chung Benjamin, Mills Margaret G, Roychoudhury Pavitra, Greninger Alexander L

Abstract excerpt

Monkeypox virus, the causative agent of the 2022 monkeypox outbreak, is a double-stranded DNA virus in the Orthopoxvirus genus of the Poxviridae family. Genes in terminal regions of Orthopoxvirus genomes mostly code for host-pathogen interaction proteins and are prone to selective pressure and modification events. Using viral whole genome sequencing, we identified twenty-five total clinical samples with...

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PMID: 36366490
DOI: 10.3390/v14112393
PMCID: PMC9695478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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