Article
A cyclin D1 (CCND1) gene polymorphism contributes to susceptibility to papillary thyroid cancer in the Turkish population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Aytekin Turkan, Aytekin Alper, Maralcan Gokturk, Gokalp M Avni, Ozen Dogukan, Borazan Ersin, Yilmaz Latif
Abstract excerpt
Cyclin D1 is an important positive regulator of the G1/S phase of the cell cycle. We investigated the association between the CCND1 G870A polymorphism and susceptibility to papillary thyroid cancer in Turkish people. This study covered 102 patients with papillary thyroid cancer and 174 healthy controls. CCND1 genotyping was determined by the PCR-RFLP method. We found that the A allele frequency was higher in the...
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