Article
Inhalable curcumin: offering the potential for translation to imaging and treatment of Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
McClure Richard, Yanagisawa Daijiro, Stec Donald, Abdollahian Dave, Koktysh Dmitry, Xhillari Dritan, Jaeger Rudolph, Stanwood Gregg, Chekmenev Eduard, Tooyama Ikuo, Gore John C, Pham Wellington
Abstract excerpt
Curcumin is a promising compound that can be used as a theranostic agent to aid research in Alzheimer's disease. Beyond its ability to bind to amyloid plaques, the compound can also cross the blood-brain barrier. Presently, curcumin can be applied only to animal models, as the formulation needed for iv injection renders it unfit for human use. Here, we describe a novel technique to aerosolize a curcumin...
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