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Article

Comparison of colorimetric assays with quantitative amino acid analysis for protein quantification of Generalized Modules for Membrane Antigens (GMMA).

Molecular biotechnology - 1 Jan 2015

Rossi Omar, Maggiore Luana, Necchi Francesca, Koeberling Oliver, MacLennan Calman A, Saul Allan, Gerke Christiane

Abstract excerpt

Genetically induced outer membrane particles from Gram-negative bacteria, called Generalized Modules for Membrane Antigens (GMMA), are being investigated as vaccines. Rapid methods are required for estimating the protein content for in-process assays during production. Since GMMA are complex biological structures containing lipid and polysaccharide as well as protein, protein determinations are not necessarily...

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Identifiers

PMID: 25223624
DOI: 10.1007/s12033-014-9804-7
PMCID: PMC4287666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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