Article
Divergent influence of microRNA-21 deletion on murine colitis phenotypes.
Inflammatory bowel diseases - 1 Nov 2014
Wu Feng, Dong Fengshi, Arendovich Nikolai, Zhang Jing, Huang Yong, Kwon John H
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) acting as negative regulators of gene expression are differentially expressed in intestinal tissues of patients with inflammatory bowel disease (IBD). Assessing the functions of miRNAs in murine colitis facilitates elucidating the role of specific miRNAs in human IBD. We aimed to determine the miRNA signature of several models of colitis and to assess the influence of miR-21 on...
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