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Article

Exploring the role of Interleukin-16 genetic variation and expression in vitiligo.

Journal of immunoassay & immunochemistry - 1 Jan 2026

El Derbaly Sara A, Mabrouk Abd-Allah Ahmed Eman, Gaber Antar Farag Azza, El-Kousy Salah M, El Sayed Ibrahim El Tantawy

Abstract excerpt

Vitiligo is a multifactorial melanocyte disease caused by immune-mediated destruction. Inflammatory cytokines are central to vitiligo pathogenesis. Interleukin-16 (IL-16) is a pro-inflammatory cytokine implicated in the recruitment and activation of T-cells (CD4+), indicating that it may play a role in autoimmune inflammation. Nevertheless, the IL-16 expression and its genetic variants in vitiligo are poorly...

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Identifiers

PMID: 42528378
DOI: 10.1080/15321819.2026.2701079

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CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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