Article
A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat.
PloS one - 1 Jan 2017
Jadeja Shahnawaz D, Mansuri Mohmmad Shoab, Singh Mala, Dwivedi Mitesh, Laddha Naresh C, Begum Rasheedunnisa
Abstract excerpt
BACKGROUND: Autoimmunity has been implicated in the destruction of melanocytes from vitiligo skin. Major histocompatibility complex (MHC) class-II linked genes proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1), involved in antigen processing and presentation have been reported to be associated with several autoimmune diseases including vitiligo. OBJECTIVES: To explore...
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