Genome-wide identification of RNA modification-related single nucleotide polymorphisms associated with rheumatoid arthritis.

doi:10.1186/s12864-023-09227-2

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Article

Genome-wide identification of RNA modification-related single nucleotide polymorphisms associated with rheumatoid arthritis.

BMC genomics - 27 Mar 2023

Wang Mimi, Wu Jingyun, Lei Shufeng, Mo Xingbo

Abstract excerpt

BACKGROUND: RNA modification plays important roles in many biological processes, such as gene expression control. The aim of this study was to identify single nucleotide polymorphisms related to RNA modification (RNAm-SNPs) for rheumatoid arthritis (RA) as putative functional variants. METHODS: We examined the association of RNAm-SNPs with RA in summary data from a genome-wide association study of 19,234 RA cases...

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Arthritis, Rheumatoid
Carrier Proteins
HLA-A Antigens
HLA-DRB1 Chains
Intracellular Signaling Peptides and Proteins
Repressor Proteins

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TNF Receptor-Associated Factor 1

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PMID: 36973646
DOI: 10.1186/s12864-023-09227-2
PMCID: PMC10045113

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