Article
Distortion of memory Vδ2 γδ T cells contributes to immune dysfunction in chronic HIV infection.
Cellular & molecular immunology - 1 Sept 2015
Li Zhen, Jiao Yanmei, Hu Yu, Cui Lianxian, Chen Dexi, Wu Hao, Zhang Jianmin, He Wei
Abstract excerpt
γδ T cells play important roles in innate immunity as the first-line of defense against infectious diseases. Human immunodeficiency virus (HIV) infection disrupts the balance between Vδ(1) T cells and Vδ(2) T cells and causes dysfunction among γδ T cells. However, the biological mechanisms and clinical consequences of this disruption require further investigation. In this study, we performed a comprehensive...
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