Article
The pigeon (Columba livia) model of spontaneous atherosclerosis.
Poultry science - 1 Nov 2014
Anderson J L, Smith S C, Taylor R L
Abstract excerpt
Multiple animal models have been employed to study human atherosclerosis, the principal cause of mortality in the United States. Each model has individual advantages related to specific pathologies. Initiation, the earliest disease phase, is best modeled by the White Carneau (WC-As) pigeon. Atherosclerosis develops spontaneously in the WC-As without either external manipulation or known risk factors. Furthermore,...
Topics
- Animals
- Atherosclerosis
- Columbidae
- Disease Models, Animal
- Disease Susceptibility
- Genetic Predisposition to Disease
- Humans
- Phenotype