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Article

Of founder populations, long QT syndrome, and destiny.

Heart rhythm - 1 Nov 2009

Brink Paul A, Schwartz Peter J

Abstract excerpt

Founder populations, characterized by a single ancestor affected by long QT syndrome (LQTS) and by a large number of individuals and families who all are related to the ancestor and thereby carry the same disease-causing mutation, represent the ideal human model for studying the role of "modifier genes" in LQTS. This article reviews some of the fundamental concepts related to founder populations and provides the...

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Source

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Identifiers

PMID: 19880070
DOI: 10.1016/j.hrthm.2009.08.036
PMCID: PMC2802718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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