A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study.

doi:10.1111/jcmm.12359

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Article

A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study.

Journal of cellular and molecular medicine - 1 Nov 2014

Zhang Weigang, Yi Xiuli, Guo Sen, Shi Qiong, Wei Chao, Li Xia, Gao Lin, Wang Gang, Gao Tianwen, Wang Lei, Li Chunying

Abstract excerpt

Epidermal growth factor receptor (EGFR), which is overexpressed in psoriatic lesions, has been proven to contribute to the hyperproliferation of keratinocytes in psoriasis. Single nucleotide polymorphisms (SNPs) involved in miRNAs that can regulate the expression of EGFR could potentially influence the development of psoriasis. The present study investigated the association between a functional SNP of rs2910164...

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PMID: 25209759
DOI: 10.1111/jcmm.12359
PMCID: PMC4224556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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