Article
Down-regulation of microRNA-146a is associated with high-risk human papillomavirus infection and epidermal growth factor receptor overexpression in penile squamous cell carcinoma.
Human pathology - 1 Mar 2017
Peta Elektra, Cappellesso Rocco, Masi Giulia, Sinigaglia Alessandro, Trevisan Marta, Grassi Angela, Di Camillo Barbara, Vassarotto Elisa, Fassina Ambrogio, Palù Giorgio, Barzon Luisa
Abstract excerpt
Dysregulation of host microRNA expression has been involved in the development and progression of human papillomavirus (HPV)-related tumors. Analysis of miR-146a expression in a series of 59 penile squamous cell carcinomas (PSCCs) showed that its levels were lower in high-risk HPV-positive than in HPV-negative PSCCs and inversely correlated with expression of epidermal growth factor receptor (EGFR), a known...
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