Article
Serum Levels of miR-146a in Patients with Psoriasis.
Molecular diagnosis & therapy - 1 Jul 2021
Leal Bárbara, Carvalho Cláudia, Ferreira Ana Marta, Nogueira Miguel, Brás Sandra, Silva Berta M, Selores Manuela, Costa Paulo P, Torres Tiago
Abstract excerpt
BACKGROUND: Psoriasis is an immune-mediated disease with interactions between genetic and environmental factors. An increasing number of studies are demonstrating the importance of microRNAs (miRNAs) in the pathogenesis of psoriasis. miR-146a, a dominant negative regulator of inflammation, has been consistently reported as overexpressed in the skin and peripheral blood mononuclear cells (PBMCs) of patients with...
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