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Lentiviral labeling of mouse and human enteric nervous system stem cells for regenerative medicine studies

8 Sept 2014

Abstract excerpt

BACKGROUND: Reliable methods of labeling human enteric nervous system (ENS) stem cells for use in novel cell replacement therapies for enteric neuropathies are lacking. Here, we explore the possibility of using lentiviral vectors expressing fluorescent reporter genes to transduce, label, and trace mouse and human ENS stem cells following transplantation into mouse gut. METHODS: Enteric nervous system precursors,...

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PMID: 25199909
DOI: 10.1111/nmo.12420

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