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Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos

10 Feb 2010

Abstract excerpt

Neural crest is a source of diverse cell types, including the peripheral nervous system. The transcription factor Sox10 is expressed throughout early neural crest. We exploited Sox10 reporter and selection markers created by homologous recombination to investigate the generation, maintenance and expansion of neural crest progenitors. Sox10-GFP-positive cells are produced transiently from mouse embryonic stem (ES)...

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PMID: 20147374
DOI: 10.1242/dev.046896

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