Epigenetic Control of Trefoil Factor Family (TFF) Peptide Expression in Human Retinoblastoma Cell Lines

Abstract excerpt

BACKGROUND: Recent studies demonstrated that epigenetic mechanisms are involved in the regulation of trefoil factor family (TFF) peptide expression in cancer. In human tissues with endogenous TFF1, TFF2 or TFF3 gene expression, the corresponding promoter is unmethylated and in organs without TFF expression, the promoter of the three genes is highly methylated. METHODS: Retinoblastoma (Rb) cell lines were treated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Helicobacter pylori-related gastroenterology studies
• Share to Immune Response and Inflammation
• Share to Immunotherapy and Immune Responses