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Article

Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development.

The Journal of biological chemistry - 24 Oct 2014

Liu Zhihui, Li Wenling, Ma Xuefei, Ding Nancy, Spallotta Francesco, Southon Eileen, Tessarollo Lino, Gaetano Carlo, Mukouyama Yoh-Suke, Thiele Carol J

Abstract excerpt

Chromosome 1p36 deletion syndrome is one of the most common terminal deletions observed in humans and is related to congenital heart disease (CHD). However, the 1p36 genes that contribute to heart disease have not been clearly delineated. Human CASZ1 gene localizes to 1p36 and encodes a zinc finger transcription factor. Casz1 is required for Xenopus heart ventral midline progenitor cell differentiation. Whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25190801
DOI: 10.1074/jbc.M114.570416
PMCID: PMC4207993

Genes

CASZ1
ABCC9
ACTA1
CKM
TNNI2
TNNT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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