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Article

Preclinical cerebrospinal fluid and volumetric magnetic resonance imaging biomarkers in Swedish familial Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Thordardottir Steinunn, Ståhlbom Anne Kinhult, Ferreira Daniel, Almkvist Ove, Westman Eric, Zetterberg Henrik, Eriksdotter Maria, Blennow Kaj, Graff Caroline

Abstract excerpt

BACKGROUND: It is currently believed that therapeutic interventions will be most effective when introduced at the preclinical stage of Alzheimer's disease (AD). This underlines the importance of biomarkers to detect AD pathology in vivo before clinical disease onset. OBJECTIVE: To examine the evolution of cerebrospinal fluid (CSF) biomarker and brain structure changes in the preclinical phase of familial AD....

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PMID: 25182737
DOI: 10.3233/JAD-140339

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PSEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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