Article
Genetic analyses of HIV-1 pol sequences from Zimbabwean patients.
The new microbiologica - 1 Jul 2014
Falasca Francesca, Temperoni Chiara, Mazzuti Laura, Lo Presti Alessandra, Ciccozzi Massimo, Di Filippo Elisa, Iaiani Giancarlo, Taliani Gloria, Turriziani Ombretta
Abstract excerpt
This study analysed the sequence of HIV-1 pol gene derived from Zimbabwean infected patients. Sequence analysis, performed on 8 samples, revealed that sequences were classified as subtype C (n=5), subtype B (n=2) and CRF01_AE (n=1). Two patients, treated with a therapeutic regimen containing NRTI/NNRTI, harboured drug resistance mutations in HIV-1 DNA. Phylogenetic analysis performed on subtype C sequences showed...
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