Article
Genetic analysis of HIV-1 isolates from Zambia and an expanded phylogenetic tree for HIV-1.
Journal of acquired immune deficiency syndromes - 1 Jan 1992
McCutchan F E, Ungar B L, Hegerich P, Roberts C R, Fowler A K, Hira S K, Perine P L, Burke D S
Abstract excerpt
Geographic variation in the HIV-1 virus is extensive but incompletely documented. We herein report the first genetic characterization of HIV-1 isolates from Zambia. The genomic region encoding the GAG polyprotein has been compared among 22 Zambian isolates and 14 North American isolates using a combination of polymerase chain reaction (PCR) and DNA sequencing methods. The Zambian isolates were similar to one...
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