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Atypical cyclins: the extended family portrait

16 Aug 2019

Abstract excerpt

Regulation of cell division is orchestrated by cyclins, which bind and activate their catalytic workmates, the cyclin-dependent kinases (CDKs). Cyclins have been traditionally defined by an oscillating (cyclic) pattern of expression and by the presence of a characteristic "cyclin box" that determines binding to the CDKs. Noteworthy, the Human Genome Sequence Project unveiled the existence of several other...

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PMID: 31420702
DOI: 10.1007/s00018-019-03262-7

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