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Germ-line exon 21 EGFR mutations, V843I and P848L, in nonsmall cell lung cancer patients

31 Aug 2014

Abstract excerpt

To the Editor: Somatic epidermal growth factor receptor (EGFR) mutations are now routinely integrated in the molecular diagnosis of nonsmall cell lung cancers (NSCLC) Thus, germ-line EGFR mutations are rarely mentioned or looked for in the context of patients with a family history of cancer, as their association with NSCLC familial cancer risk is not well established. Moreover, the predictive value of these...

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PMID: 25176975
DOI: 10.1183/09059180.00009313

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