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Article

Two rare exon 21 EGFR mutations in patients treated with gefitinib.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2013

Mompradé Elisabet, Arriola Edurne, Martínez-Avilés Luz

Abstract excerpt

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Share to Adenocarcinoma
Share to ErbB Receptors
Share to Gefitinib
Share to Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23486275
DOI: 10.1097/JTO.0b013e318286cf9e

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Research trail→

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Two rare exon 21 EGFR mutations in patients treated with gefitinib.PMID 23486275Read ↗

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Primary resistance to gefitinib in a patient with lung adenocarcinoma harboring an EGFR exon 19 L747-A750>P mutation.Semantic proximity Read ↗

Evaluation of treatment efficacy of tyrosine kinase inhibitors in rare single EGFR Exon 21 L861Q mutation; single center experience.Semantic proximity Read ↗

Good response to gefitinib in a lung adenocarcinoma harboring a heterozygous complex mutation of L833V and H835L in epidermal growth factor receptor gene.Semantic proximity Read ↗

Acquired gefitinib-resistant mutation of EGFR in a chemonaive lung adenocarcinoma harboring gefitinib-sensitive mutation L858R.Semantic proximity Read ↗

Novel EGFR Exon 18 (G721R) Mutation in a Patient with Non-Small Cell Lung Carcinoma with Lack of Response to Afatinib.Semantic proximity Read ↗

Two Patients Having NSCLC With Novel Duplication Mutation in Their EGFR Gene (p.I740_K745dupIPVAIK) and Their Response to Osimertinib.Semantic proximity Read ↗

Epidermal Growth Factor Receptor (EGFR) Mutation in Exon 19 (p.E749Q) Confers Resistance to Gefitinib in One Patient With Lung Adenocarcinoma.Semantic proximity Read ↗

Good Clinical Response to Gefitinib in a Non-small Cell Lung Cancer Patient Harboring a Rare Somatic Epidermal Growth Factor Gene Point Mutation; Codon 768 AGC > ATC in Exon 20 (S768I)Semantic proximity Read ↗

An uncommon insertion mutation in exon 19 of EGFR showed stable disease after TKI treatment.Semantic proximity Read ↗

Activity of gefitinib in a non-small-cell lung cancer patient with both activating and resistance EGFR mutations.Semantic proximity Read ↗

Response to Erlotinib in a Patient with Compound EGFR L747S and Exon 19 Deletion.Semantic proximity Read ↗

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