Article
Adenocarcinoma with epidermal growth factor receptor gene mutations in three siblings.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2008
Sakakibara Tomohiro, Saijo Yasuo, Fukuhara Tatsuro, Gomi Kazunori, Inoue Akira, Ishimoto Osamu, Sugawara Shunichi, Nukiwa Toshihiro
Abstract excerpt
Sensitivity to an inhibitor of epidermal growth factor receptor (EGFR) kinase strongly correlates with EGFR somatic mutations in non-small cell lung cancer. These mutations are frequently found in patients with adenocarcinoma, never- or light-smokers, women, and East Asians. In this study, we sho...
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