Article
MTHFR polymorphisms and serum cobalamin affect plasma homocysteine concentrations differentially in females and males.
Molecular medicine reports - 1 Nov 2014
Nilsson Torbjörn K, Böttiger Anna K, Henríquez Patricia, Serra Majem Lluís
Abstract excerpt
A total of 523 subjects (297 females and 226 males) from the Canary Islands Nutrition Study (ENCA) were studied in order to examine the effect of the MTHFR 677C>T, 1298A>C and 1793G>A polymorphisms, adjusted for age, serum (S)‑folate and S‑cobalamin levels, on total plasma homocysteine concentrations (tHcy). Genotyping was performed with Pyrosequencing® technology. The MTHFR 677T‑allele was associated with...
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