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Article

Single nucleotide polymorphisms in homocysteine metabolism pathway genes: association of CHDH A119C and MTHFR C677T with hyperhomocysteinemia.

Circulation. Cardiovascular genetics - 1 Dec 2009

Kumar Jitender, Garg Gaurav, Kumar Arun, Sundaramoorthy Elayanambi, Sanapala Krishna Rao, Ghosh Saurabh, Karthikeyan Ganesan, Ramakrishnan Lakshmy, Sengupta Shantanu

Abstract excerpt

BACKGROUND: An elevated level of homocysteine (hyperhomocysteinemia) has been implicated as an independent risk factor for cardiovascular diseases. Deficiency of dietary factors like vitamin B(12), folate, and genetic variations can cause hyperhomocysteinemia. The prevalence of hyperhomocysteinemia in the Indian population is likely to be high because most Indians adhere to a vegetarian diet, deficient in vitamin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20031640
DOI: 10.1161/CIRCGENETICS.108.841411

Genes

CHDH
MTHFR

Variants

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