Article
Association of polymorphisms in AGTR1 and AGTR2 genes with primary aldosteronism in the Chinese Han population.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2015
Wu Zhun, Huang Chao, Zhou Tingting, Lin Jinglai, Zhang Kaiyan, Li Wei, Zheng Jiaxin, Chen Bin, Wang Baojun, Zhang Xu, Xing Jinchun
Abstract excerpt
HYPOTHESIS: Polymorphisms in angiotensin II type-1/2 receptor genes (AGTR1/AGTR2) may be involved in the pathogenesis of primary aldosteronism. The present study aims to reveal some loci susceptible to the disease on the genes in a group of Chinese Han nationality. MATERIALS AND METHODS: A case-control study was conducted in 202 patients and 188 controls. Ten tagging SNPs on AGTR1/AGTR2 were genotyped for all...
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