Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome

30 Aug 2014

Abstract excerpt

The hedgehog (Hh) signaling pathway is considered to be a major signal transduction pathway during embryonic development, but it usually shuts down after birth. Aberrant Sonic hedgehog (Shh) activation during adulthood leads to neoplastic growth. Basal cell carcinoma (BCC) of the skin is driven by this pathway. Here, we summarize information related to the pathogenesis of this neoplasm, discuss pathways that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer and Skin Lesions
Share to Genetic and rare skin diseases.
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25172843
DOI: 10.1158/0008-5472.can-14-1666

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sonic Hedgehog Signaling in Basal Cell Nevus SyndromePMID 25172843Read ↗

The molecular genetics underlying basal cell carcinoma pathogenesis and links to targeted therapeutics.Semantic proximity Read ↗

Correlations between the Sonic Hedgehog pathway and basal cell carcinoma.Semantic proximity Read ↗

Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.Semantic proximity Read ↗

Targeting the hedgehog pathway to treat basal cell carcinoma.Semantic proximity Read ↗

Hedgehog signalling in skin development and cancerSemantic proximity Read ↗

Basal Cell Carcinoma and the Carcinogenic Role of Aberrant Hedgehog SignalingSemantic proximity Read ↗

Novel Approaches in Non-Melanoma Skin Cancers—A Focus on Hedgehog Pathway in Basal Cell Carcinoma (BCC)Semantic proximity Read ↗

The Role of the Hedgehog Signaling Pathway in the Development of Basal Cell Carcinoma and Opportunities for TreatmentSemantic proximity Read ↗

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in gorlin syndromeSemantic proximity Read ↗

Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients.Semantic proximity Read ↗

Basal cell nevus syndrome.Semantic proximity Read ↗

Molecular Mechanisms and Targeted Therapies of Advanced Basal Cell CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.