Article
Correlations between the Sonic Hedgehog pathway and basal cell carcinoma.
International journal of dermatology - 1 Nov 2007
Lupi Omar
Abstract excerpt
The Hedgehog (HH) family of intercellular signaling proteins has some essential functions in patterning both invertebrate and vertebrate embryos. Identified as an important regulator of segment polarity and tissue organization in flies, the HH pathway can also play a significant role in human development and in cutaneous carcinogenesis. The family received their name because when the D. melanogaster HH protein...
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