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Article

Sp7/Osterix induces the mouse pro-α2(I) collagen gene (Col1a2) expression via the proximal promoter in osteoblastic cells.

Biochemical and biophysical research communications - 26 Sept 2014

Yano Hiroyuki, Hamanaka Ryoji, Nakamura-Ota Miki, Adachi Sawako, Zhang Juan Juan, Matsuo Noritaka, Yoshioka Hidekatsu

Abstract excerpt

Bone is essentially composed of two components, hydroxyapatite and extracellular matrix proteins. The extracellular matrix of bone is primary composed of collagen, mostly type I collagen, with lesser amounts of other types of collagen such as type V collagen. Osteoblast differentiation is a multi-step process in which many classes of factors function in a coordinated manner. Sp7/Osterix, which binds to G/C-rich...

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PMID: 25172663
DOI: 10.1016/j.bbrc.2014.08.100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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