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Article

NELL-1, an Osteoinductive Factor, Is a Direct Transcriptional Target of Osterix

13 Sept 2011

Abstract excerpt

NELL-1 is a novel secreted protein associated with premature fusion of cranial sutures in craniosynostosis that has been found to promote osteoblast cell differentiation and mineralization. Our previous study showed that Runx2, the key transcription factor in osteoblast differentiation, transactivates the NELL-1 promoter. In this study, we evaluated the regulatory involvement and mechanisms of Osterix, an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21931789
DOI: 10.1371/journal.pone.0024638

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Research trail→

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NELL-1, an Osteoinductive Factor, Is a Direct Transcriptional Target of OsterixPMID 21931789Read ↗

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