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Article

RUNX2 co‐operates with EGR1 to regulate osteogenic differentiation through Htra1 enhancers

23 Apr 2020

Abstract excerpt

Runt-related transcription factor 2 (Runx2) has been shown to regulate osteoblast differentiation by directly or indirectly regulating numerous osteoblast-related genes. However, our understanding of the transcriptional mechanisms of RUNX2 is mainly restricted to its transactivation, while the mechanism underlying its inhibitory effect during osteoblast differentiation remains largely unknown. Here, we...

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PMID: 32324256
DOI: 10.1002/jcp.29704

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