Article
Relationship between European mitochondrial haplogroups and chronic renal allograft rejection in patients with kidney transplant.
International journal of medical sciences - 1 Jan 2014
Jiménez-Sousa María Angeles, Tamayo Eduardo, Guzmán-Fulgencio María, Fernández-Rodríguez Amanda, Heredia-Rodriguez María, García-Álvarez Mónica, Bermejo-Martin Jesús F, Pineda-Tenor Daniel, Ruiz-Granado Patricia, Alvarez-Fuente Elisa, Gómez-Sanchez Esther, Gómez-Herreras José I, Resino Salvador
Abstract excerpt
Mitochondrial DNA variants may contribute to differences in mitochondrial function, leading to an altered immune system. The aim of this study was to analyze the relationship between mtDNA haplogroups and the development of chronic allograft dysfunction in patients with kidney transplant. A retrospective observational study was carried out on 261 patients who received kidney transplant (114 had stable transplant...
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