Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next-generation sequencing of the mitochondrial genome and association with IgA nephropathy in a renal transplant population.

Scientific reports - 9 Dec 2014

Douglas Adam P, Vance Dwaine R, Kenny Elaine M, Morris Derek W, Maxwell Alexander P, McKnight Amy Jayne

Abstract excerpt

Kidneys are highly aerobic organs that are critically dependent on the normal functioning of mitochondria. Genetic variations disrupting mitochondrial function are associated with multifactorial disorders including kidney disease. This study sequenced the entire mitochondrial genome in a renal transplant cohort of 64 individuals, using next-generation sequencing, to evaluate the association of genetic variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Mitochondrial
Share to Genome, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis, IGA

Share to High-Throughput Nucleotide Sequencing

Share to Kidney Failure, Chronic

Share to Kidney Transplantation

Share to Linkage Disequilibrium

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 25488329
DOI: 10.1038/srep07379
PMCID: PMC4260226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next-generation sequencing of the mitochondrial genome and association with IgA nephropathy in a renal transplant population.PMID 25488329Read ↗

Genetic variants affecting mitochondrial function provide further insights for kidney disease.Semantic proximity Read ↗

IgA nephropathy is associated with elevated urinary mitochondrial DNA copy numbersSemantic proximity Read ↗

Mitochondrial genetic variation and risk of chronic kidney disease and acute kidney injury in UK Biobank participants.Semantic proximity Read ↗

Genome-Wide Study Updates in the International Genetics and Translational Research in Transplantation Network (iGeneTRAiN)Semantic proximity Read ↗

Next-generation sequencing for research and diagnostics in kidney diseaseSemantic proximity Read ↗

Mitochondrial DNA copy number in peripheral blood of IgA nephropathy: a cross-sectional studySemantic proximity Read ↗

MT-ND1 Variants and Protective Haplotypes in Egyptian Chronic Kidney Disease: An Integrated Targeted Mitochondrial AnalysisSemantic proximity Read ↗

Diagnostic Utility of Exome Sequencing for Kidney DiseaseSemantic proximity Read ↗

Mitochondrial DNA and Kidney FunctionSemantic proximity Read ↗

Renal involvement is frequent in adults with primary mitochondrial disorders: an observational studySemantic proximity Read ↗

Distinct methylation patterns in genes that affect mitochondrial function are associated with kidney disease in blood‐derived DNA from individuals with Type 1 diabetesSemantic proximity Read ↗

Genetic Susceptibility to Chronic Kidney Disease – Some More Pieces for the Heritability PuzzleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.