Article
miRNAs can be generally associated with human pathologies as exemplified for miR-144.
BMC medicine - 3 Dec 2014
Keller Andreas, Leidinger Petra, Vogel Britta, Backes Christina, ElSharawy Abdou, Galata Valentina, Mueller Sabine C, Marquart Sabine, Schrauder Michael G, Strick Reiner, Bauer Andrea, Wischhusen Jörg, Beier Markus, Kohlhaas Jochen, Katus Hugo A, Hoheisel Jörg, Franke Andre, Meder Benjamin, Meese Eckart
Abstract excerpt
BACKGROUND: miRNA profiles are promising biomarker candidates for a manifold of human pathologies, opening new avenues for diagnosis and prognosis. Beyond studies that describe miRNAs frequently as markers for specific traits, we asked whether a general pattern for miRNAs across many diseases exists. METHODS: We evaluated genome-wide circulating profiles of 1,049 patients suffering from 19 different cancer and...
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