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Article

CacyBP/SIP binds ERK1/2 and affects transcriptional activity of Elk-1.

Biochemical and biophysical research communications - 27 Feb 2009

Kilanczyk Ewa, Filipek Slawomir, Jastrzebska Beata, Filipek Anna

Abstract excerpt

In this work we showed for the first time that mouse CacyBP/SIP interacts with extracellular signal regulated kinases 1 and 2 (ERK1/2). We also established that a calcium binding protein, S100A6, competes for this interaction. Moreover, the E217K mutant of CacyBP/SIP does not bind significantly to ERK1/2 although it retains the ability to interact with S100A6. Molecular modeling shows that the E217K mutation in...

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Identifiers

PMID: 19166809
DOI: 10.1016/j.bbrc.2009.01.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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